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1

A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates

Hannu Mönkkönen, Seppo Auriola, Petri Lehenkari, Maarit Kellinsalmi, Ilmo E Hassinen, Jouko Vepsäläinen, Jukka Mönkkönen

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 282 KB

english, 2006

2

MODIFICATION OF METABOLIC EFFECTS OF ETHANOL BY FRUCTOSE

Reino H. Ylikahri, Matti T. Kähönen, Ilmo Hassinen

Journal:

Journal of Internal Medicine

Year:

1972

Language:

english

File:

PDF, 688 KB

english, 1972

3

Modeling of human pathogenic mutations in Escherichia coli complex I reveals a sensitive region in the fourth inside loop of NuoH

Pilvi Maliniemi, Marko Kervinen, Ilmo E. Hassinen

Journal:

Year:

2009

Language:

english

File:

PDF, 601 KB

english, 2009

4

Analysis of functional consequences of haplogroup J polymorphisms m.4216T > C and m.3866T > C in human MT-ND1: Mutagenesis of homologous positions in Escherichia coli

Reetta Hinttala, Marko Kervinen, Johanna Uusimaa, Pilvi Maliniemi, Saara Finnilä, Heikki Rantala, Anne M. Remes, Ilmo E. Hassinen, Kari Majamaa

Journal:

Year:

2010

Language:

english

File:

PDF, 212 KB

english, 2010

5

Absorption spectrophotometry of perfused rat liver applied to fructose-induced inhibition of respiration

Ilmo Hassinen, Reino H. Ylikahri

Journal:

Biochemical and Biophysical Research Communications

Year:

1970

Language:

english

File:

PDF, 385 KB

english, 1970

6

Metabolic interactions of fructose and ethanol in perfused liver of normal and thyroxine-treated rats

Reino H. Ylikahri, Ilmo E. Hassinen, Matti T. Kähönen

Journal:

Year:

1971

Language:

english

File:

PDF, 1.04 MB

english, 1971

7

Effects of pathogenic mutations in membrane subunits of mitochondrial Complex I on redox activity and proton translocation studied by modeling in Escherichia coli

Pätsi, Jukka, Kervinen, Marko, Kytövuori, Laura, Majamaa, Kari, Hassinen, Ilmo E.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.81 MB

english, 2015

8

Signaling and regulation through the NAD+ and NADP+ networks

Hassinen, Ilmo E.

Journal:

Antioxidants & Redox Signaling

Year:

2017

Language:

english

File:

PDF, 882 KB

english, 2017

9

Cytoskeletal structure of myoblasts with the mitochondrial DNA 3243A→G mutation and of osteosarcoma cells with respiratory chain deficiency

Harri Rusanen, Johanna Annunen, Heli Ylä-Outinen, Aino Laurila, Juha Peltonen, Ilmo E. Hassinen, Kari Majamaa

Journal:

Year:

2002

Language:

english

File:

PDF, 1.11 MB

english, 2002

10

Oxygen and substrate dependence of hepatic cellular respiration: Sinusoidal oxygen gradient and effects of ethanol in isolated perfused liver and hepatocytes

Eija M. Kekonen, V. Pekka Jauhonen, Ilmo E. Hassinen

Journal:

Journal of Cellular Physiology

Year:

1987

Language:

english

File:

PDF, 1.00 MB

english, 1987

11

A reflectance spectrophotometer-surface fluorometer suitable for monitoring changes in hemoprotein spectra and fluorescence of flavins and nicotinamide nucleotides in intact tissues

Ilmo Hassinen, Timo Jämsä

Journal:

Analytical Biochemistry

Year:

1982

Language:

english

File:

PDF, 607 KB

english, 1982

12

Enzymatic assay for 3-hydroxyacyl-CoA and 2-trans-enoyl-CoA intermediates of β-oxidation

Pirjo M. Latipää, Ilmo E. Hassinen, J. Kalervo Hiltunen

Journal:

Analytical Biochemistry

Year:

1988

Language:

english

File:

PDF, 489 KB

english, 1988

13

Lucigenin and coelenterazine as superoxide probes in mitochondrial and bacterial membranes

Marko Kervinen, Jukka Pätsi, Moshe Finel, Ilmo E Hassinen

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 190 KB

english, 2004

14

POLG1p.R722H mutation associated with multiple mtDNA deletions and a neurological phenotype

Tuomas Komulainen, Reetta Hinttala, Mikko Kärppä, Leila Pajunen, Saara Finnilä, Hannu Tuominen, Heikki Rantala, Ilmo Hassinen, Kari Majamaa, Johanna Uusimaa

Journal:

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

15

Redistribution of glucose uptake by chronic exercise, measured in isolated perfused rat hearts

Heikki Kainulainen, Timo E. S. Takala, Ilmo E. Hassinen, Veikko Vihko

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1985

Language:

english

File:

PDF, 664 KB

english, 1985

16

Sequence analysis of nuclear genes encoding functionally important complex I subunits in children with encephalomyopathy

Reetta Hinttala, Johanna Uusimaa, Anne M. Remes, Heikki Rantala, Ilmo E. Hassinen, Kari Majamaa

Journal:

Journal of Molecular Medicine

Year:

2005

Language:

english

File:

PDF, 183 KB

english, 2005

17

Ischaemic preconditioning and a mitochondrial KATPchannel opener both produce cardioprotection accompanied by F1F0-ATPase inhibition in early ischaemia

Antti Ala-Rämi, Kari V. Ylitalo, Ilmo E. Hassinen

Journal:

Basic Research in Cardiology

Year:

2003

Language:

english

File:

PDF, 123 KB

english, 2003

18

Hearing impairment in patients with 3243A→G mtDNA mutation: phenotype and rate of progression

Seija Uimonen, Jukka S. Moilanen, Martti Sorri, Ilmo E. Hassinen, Kari Majamaa

Journal:

Year:

2001

Language:

english

File:

PDF, 63 KB

english, 2001

19

Homozygous W748S mutation in the POLG1 gene in patients with juvenile-onset Alpers syndrome and status epilepticus

Johanna Uusimaa, Reetta Hinttala, Heikki Rantala, Markku Päivärinta, Riitta Herva, Matias Röyttä, Heidi Soini, Jukka S. Moilanen, Anne M. Remes, Ilmo E. Hassinen, Kari Majamaa

Journal:

Year:

2008

Language:

english

File:

PDF, 242 KB

english, 2008

20

Frequency of mitochondrial DNA point mutations among patients with familial sensorineural hearing impairment

Lehtonen, Mervi S, Uimonen, Seija, Hassinen, Ilmo E, Majamaa, Kari

Journal:

European Journal of Human Genetics

Year:

2000

Language:

english

File:

PDF, 65 KB

english, 2000

21

Role of cellular energetics in ischemia-reperfusion and ischemic preconditioning of myocardium

Ilmo E. Hassinen, Klaus H. Vuorinen, Kari Ylitalo, Antti Ala-Rämi

Journal:

Molecular and Cellular Biochemistry

Year:

1998

Language:

english

File:

PDF, 182 KB

english, 1998

22

Metabolic interventions against complex I deficiency in MELAS syndrome

Kari Majamaa, Harri Rusanen, Anne Remes, Ilmo E. Hassinen

Journal:

Molecular and Cellular Biochemistry

Year:

1997

Language:

english

File:

PDF, 145 KB

english, 1997

23

Regulation of cellular respiration in myoglobin-deficient mouse heart

Erkki V. Liimatta, Axel Gödecke, Jürgen Schrader, Ilmo E. Hassinen

Journal:

Molecular and Cellular Biochemistry

Year:

2004

Language:

english

File:

PDF, 399 KB

english, 2004

24

Effects of ethanol metabolites on intermediary metabolism in heart muscle

Keijo J. Peuhkurinen, Kai T. Kiviluoma, J.Kalervo Hiltunen, Timo E.S. Takala, Ilmo E. Hassinen

Journal:

Pharmacology Biochemistry and Behavior

Year:

1983

Language:

english

File:

PDF, 393 KB

english, 1983

25

Mitochondrial respiratory control in the myocardium

Ilmo E Hassinen

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics

Year:

1986

Language:

english

File:

PDF, 1.44 MB

english, 1986

26

LHON/MELAS overlap mutation in ND1 subunit of mitochondrial complex I affects ubiquinone binding as revealed by modeling in Escherichia coli NDH-1

Jukka Pätsi, Pilvi Maliniemi, Salla Pakanen, Reetta Hinttala, Johanna Uusimaa, Kari Majamaa, Thomas Nyström, Marko Kervinen, Ilmo E. Hassinen

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2012

Language:

english

File:

PDF, 642 KB

english, 2012

27

Dual probe fluorescence monitoring of intracellular free calcium during ischemia in mouse heart by using continuous compensation for pH dependence of the dissociation constant of Fura-2, and the interference of myoglobin

Erkki Liimatta, Anu M. Kantola, Ilmo E. Hassinen

Journal:

Journal of Biochemical and Biophysical Methods

Year:

2007

Language:

english

File:

PDF, 382 KB

english, 2007

28

Acetoin as a Metabolite of Ethanol

By Ilmo Hassinen

Journal:

Acta Physiologica

Year:

1963

Language:

english

File:

PDF, 400 KB

english, 1963

29

Effect of Hypoxia on Mitochondrial Mass and Cytochrome Concentrations in Rat Heart and Liver during Postnatal Development

Vuokko L. Kinnula, Ilmo Hassinen

Journal:

Acta Physiologica

Year:

1977

Language:

english

File:

PDF, 310 KB

english, 1977

30

Effect of chronic hypoxia on hepatic triacylglycerol concentration and mitochondrial fatty acid oxidizing capacity in liver and heart

Vuokko L. Kinnula, Ilmo Hassinen

Journal:

Acta Physiologica

Year:

1978

Language:

english

File:

PDF, 581 KB

english, 1978

31

Hepatic triacylglycerol and fatty-acid biosynthesis during hypoxia in vivo

Vuokko L. Kinnula, Markku J. Savolainen, Ilmo Hassinen

Journal:

Acta Physiologica

Year:

1978

Language:

english

File:

PDF, 465 KB

english, 1978

32

Redox state ol the cellular free NAD pools, phosphorylation state of the adenylate system and the (Na+-K+)-stimulated ATP-ase in rat liver

Vuokko L. Kinnula, Ilmo Hassinen

Journal:

Acta Physiologica

Year:

1978

Language:

english

File:

PDF, 519 KB

english, 1978

33

Effects of hypoxia and fasting on the cytochrome concentration in intestinal epithelial villous cell mitochondria: Role of changes in the life-span of the cells

VUOKKO L. KINNULA, ILMO E. HASSINEN

Journal:

Acta Physiologica

Year:

1981

Language:

english

File:

PDF, 474 KB

english, 1981

34

Cardiac abnormalities in patients with mitochondrial DNA mutation 3243A>G

Kirsi Majamaa-Voltti, Keijo Peuhkurinen, Marja-Leena Kortelainen, Ilmo E Hassinen, Kari Majamaa

Journal:

BMC Cardiovascular Disorders

Year:

2002

Language:

english

File:

PDF, 257 KB

english, 2002

35

Kearns-Sayre Syndrome Case Presenting a Mitochondrial DNA Deletion with Unusual Direct Repeats and a Rudimentary RNAase Mitochondrial Ribonucleotide Processing Target Sequence

Anne M. Remes, Keijo J. Peuhkurinen, Riitta Herva, Kari Majamaa, Ilmo E. Hassinen

Journal:

Year:

1993

File:

PDF, 163 KB

1993

36

Contribution of Endothelium and Cardiomyocytes to Hypoxia-Induced Adenosine Release

M.J.Pekka Raatikainen, Keijo J. Peuhkurinen, Ilmo E. Hassinen

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1994

File:

PDF, 835 KB

1994

37

Intracellular Free Calcium and Mitochondrial Membrane Potential in Ischemia/Reperfusion and Preconditioning

Kari V Ylitalo, Antti Ala-Rämi, Erkki V Liimatta, Keijo J Peuhkurinen, Ilmo E Hassinen

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2000

Language:

english

File:

PDF, 224 KB

english, 2000

38

Effect of exogenous fructose-1,6-bisphosphate on glycolysis in the isolated perfused rat heart

E.Matti Nuutinen, Giuseppe Lazzarino, Bruno Giardina, Ilmo E. Hassinen

Journal:

American Heart Journal

Year:

1991

Language:

english

File:

PDF, 599 KB

english, 1991

39

Regulation of cellular respiration by thyroid hormone. Spectroscopic evidence of mitochondrial control in intact rat liver

Ilmo E. Hassinen, Reino H. Ylikahri, Matti T. Kähönen

Journal:

Archives of Biochemistry and Biophysics

Year:

1971

Language:

english

File:

PDF, 645 KB

english, 1971

40

Effect of ethanol on hepatic phosphatidate phosphohydrolase: Dose-dependent enzyme induction and its abolition by adrenalectomy and pyrazole treatment

Markku J. Savolainen, Ilmo E. Hassinen

Journal:

Archives of Biochemistry and Biophysics

Year:

1980

Language:

english

File:

PDF, 533 KB

english, 1980

41

Precursor supply and hepatic enzyme activities as regulators of triacylglycerol synthesis in isolated hepatocytes and perfused liver

Anja H. Pikkukangas, Ritva A. Väänänen, Markku J. Savolainen, Ilmo E. Hassinen

Journal:

Archives of Biochemistry and Biophysics

Year:

1982

Language:

english

File:

PDF, 891 KB

english, 1982

42

Respiratory control in isolated perfused rat heart. Role of the equilibrium relations between the mitochondrial electron carriers and the adenylate system

Ilmo E. Hassinen, Kalervo Hiltunen

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1975

Language:

english

File:

PDF, 644 KB

english, 1975

43

Plasma membrane phosphate transport and extracellular phosphate concentration in the regulation of cellular respiration in isolated perfused rat heart

Matti Nuutinen, Ilmo Hassinen

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1981

Language:

english

File:

PDF, 722 KB

english, 1981

44

Compartmentation of citrate in relation to the regulation of glycolysis and the mitochondrial transmembrane proton electrochemical potential gradient in isolated perfused rat heart

Risto A. Kauppinen, J.Kalervo Hiltunen, Ilmo E. Hassinen

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1982

Language:

english

File:

PDF, 476 KB

english, 1982

45

Mitochondrial membrane potential, transmembrane difference in the NAD+ redox potential and the equilibrium of the glutamate-aspartate translocase in the isolated perfused rat heart

Risto A. Kauppinen, J.Kalervo Hiltunen, Ilmo E. Hassinen

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1983

Language:

english

File:

PDF, 702 KB

english, 1983

46

Mechanism of fatty acid effect on myocardial oxygen consumption. A phosphorus NMR study

Ilmo Hassinen, Kinji Ito, Shoko Nioka, Britton Chance

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1990

Language:

english

File:

PDF, 697 KB

english, 1990

47

5′-nucleotidase activity and adenosine production in rat liver mitochondria

M.J. Pekka Raatikainen, Keijo J. Peuhkurinen, Kai T. Kiviluoma, J. Kalervo Hiltunen, Ilmo E. Hassinen

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1992

Language:

english

File:

PDF, 801 KB

english, 1992

48

Reaction of dicyclohexylcarbodiimide with mitochondrial proteins

Ilmo E. Hassinen, Pertti T. Vuokila

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1993

Language:

english

File:

PDF, 1.66 MB

english, 1993

49

Regulation of fatty acid oxidation in heart muscle effects of pyruvate and dichloroacetate

Pirjo M. Latipää, J.Kalervo Hiltunen, Keijo J. Peuhkurinen, Ilmo E. Hassinen

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1983

Language:

english

File:

PDF, 1.00 MB

english, 1983

50

Effect of disulfiram (tetraethylthiuram disulfide) on mitochondrial oxidations

Journal:

Biochemical Pharmacology

Year:

1966

Language:

english

File:

PDF, 371 KB

english, 1966